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Damn you human-murine chimeric monoclonal antibody!


This happened almost over night. Day one I was a wee bit zitty. Day two brought mega-spotification. It looks worse when I see it in the mirror and angle my head to get the light just right. In fact this picture doesn’t do it justice at all. It’s much worse!

This is one of the side-effects of my chemo therapy. Cetuximab is an epidermal growth factor receptor (EGFR) inhibitor. Cancer causes cells to divide uncontrollably. Cetuximab turns off the uncontrolled growth. However the mechanism causing the skin problems is the same as the mechanism that suppresses the tumour. In other words if you want a belt & braces (suspenders) approach you have to live with the acne.

Sadly some patients would rather stop treatment than live with the rash. Luckily for me I blog about it and that makes me feel better. My only problem is that I want to explain it to people.

“I don’t normally look this spotty. I have cancer you know. Why are you looking at me like that?”

8 comments to Damn you human-murine chimeric monoclonal antibody!

  • Karen

    Les, you make me laugh or smile every day! Cheers!

  • Ragni

    So I said to a Scotsman ‘did you have terrible spots as a kid?’ He said ‘ac ne’

  • Fankler

    Oh how right you are Lisa P. Sitting here waiting for radiation I am always reminded how lucky I am. I’m not in a wheelchair with a hole in my throat. I’m not alone struggling to get here. I don’t have a job to worry about. In comparison I’ve got it made. I’m grateful 🙂

  • LisaP

    Acne or Cancer? It’s not a bad choice:). Hope you are feeling OK and pushing through the chemo. Let us know if we can do anything for you, Eva or Izzy and gang!!

  • Fankler

    Thanks Kurt. I know you’ve been thru all this before. I sometimes feel it’s harder for those caring for us.

  • Kurt

    Don’t explain, just let them wonder. Consider it a social experiment. Do people avoid eye contact? Give ’em a charming smile (you can do it, really) and see if they respond, or squirm. And remember it’s temporary; you’ll have decades more lookin’ good in exchange for this inconvenience.

  • Fankler

    You are sooo right! How funny. And then in the car, trying to explain that I couldn’t be available in the morning because “I have to have a medical procedure every morning.” Like I’m some enema freak.

  • Mrs. Hall

    I could tell you were thiiiiiiiis close to telling our waitress today. 🙂

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